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  • Suzhou Vitajoy Biotech Co.,Ltd

  •  [Jiangsu,China]
  • Business Type:Agent , Distributor/Wholesaler , Manufacturer , Trade Company
  • Main Mark: Americas , East Europe , Europe , Middle East , North Europe , Worldwide
  • Exporter:91% - 100%
  • Certs:ISO9001, ISO9002, SSA
  • Description:Protected Amino Acid,High Purity Alanine,Alanine Powder,Valine Powder
Suzhou Vitajoy Biotech Co.,Ltd Protected Amino Acid,High Purity Alanine,Alanine Powder,Valine Powder
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Protected amino acid

Product categories of Protected amino acid, we are specialized manufacturers from China, Protected Amino Acid, High Purity Alanine suppliers/factory, wholesale high-quality products of Alanine Powder R & D and manufacturing, we have the perfect after-sales service and technical support. Look forward to your cooperation!
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BOC-L-Tyrosine
BOC-L-Tyrosine

Model No. : Pharma Grade

Product Description Product name: BOC-L-Tyrosine Appearance: White or almost crystalline powder or colorless crystals CAS NO.3978-80-1 Molecular Formula:C14H19NO5 Molecular Weight:281.3 g/mol Description: For biochemical reagents, peptide synthesis....

Wholesale Various High Quality of Protected Amino Acid
CBZ-L-Valine
CBZ-L-Valine

Model No. : Pharma Grade

Product Description Product name:CBZ-L-Valine Appearance: White or almost crystalline powder or colorless crystals CAS NO.:1149-26-4 Molecular Formula: C13H17NO4 Molecular Weight:251.28 g/mol Description: Lab test use. Main Functions The present...

China High Purity Alanine Brands
CBZ-L-Alanine
CBZ-L-Alanine

Model No. : Pharma Grade

Product Description Product name:CBZ-L-Alanine Appearance: White or almost crystalline powder or colorless crystals CAS NO.:1142-20-7 Molecular Formula: C11H13NO4 Molecular Weight:251.28 g/mol Description: For lab used as biochemical reagents,...

New design of Alanine Powder
CBZ-L-Glutamine
CBZ-L-Glutamine

Model No. : Pharma Grade

Product Description Product name:CBZ-L-Glutamine Appearance: White or almost crystalline powder or colorless crystals CAS NO.:2650-64-8 Molecular Formula: C13H16N2O5 Molecular Weight:280.28 g/mol Description: For biochemical reagents, peptide...

Cheap Valine Powder from China
BOC-L-Histidine
BOC-L-Histidine

Model No. : Pharma Grade

Product Description Product name: BOC-L-Valine Appearance: White or almost crystalline powder or colorless crystals CAS NO.17791-52-5 Molecular Formula:C11H17N3O4 Molecular Weight:255.27 g/mol Description: For biochemical reagents, peptide...

High Quality Protected Amino Acid China Manufacturer

China Protected amino acid Suppliers

Amino Acids have reactive moieties at the N- and C-termini, which facilitates Amino Acid coupling during synthesis. Many amino acids also have reactive side chain functional groups, which can interact with free termini or other side chain groups during synthesis and peptide elongation and negatively influence yield and purity. To facilitate proper amino acid synthesis with minimal side chain reactivity, chemical groups have been developed to bind to specific amino acid functional groups and block, or protect, the functional group from nonspecific reactions. These protecting groups, while vast in nature, can be separated into three groups, as follows:


N-terminal protecting groups
C-terminal protecting groups (mostly used in liquid-phase synthesis)
Side chain protecting groups

We offer a diverse selection of amino acids with protecting groups such as Fmoc, Boc and Cbz.

Boc-amino acids are generally crystalline solids, and their particular suitability for SPPS has been clearly demonstrated. The Boc group has been used for the solid-phase synthesis (SPS) of a number of relevant peptides using the so-called Boc/Bn strategy. The most common removal conditions for Boc are 25-50% TFA in DCM, but other acids, such as 1 M trimethylsilyl chloride (TMS-Cl) phenol in DCM,274 M HCl in dioxane, and 2 M MeSO3H in dioxane, have been successfully used for solution and solid-phase synthetic strategies. The Boc group is stable to bases and nucleophiles as well as to catalytic hydrogenation.


9-Fluorenylmethoxycarbonyl (Fmoc). It is removed by bases (mainly secondary amines, because they are better at capturing the dibenzofulvene generated during the re-moval) and is stable to acids. It is not completely stable tothe catalytic hydrogenolysis treatment required to remove benzyl esters when Pd/C or PtO2 are used as catalysts. The most selective catalyst is Pd/BaSO4. Solution removal is done by liquid NH3(10 h) and morpholine or piperidine(within minutes), 10% diethylamine (DEA), dimethylaceta-mide (DMA) (2 h),53and polymeric (silica gel or polystyrene)secondary amines (i.e., piperazine, piperidine) in organic solvents. This was applied for the first time for SPPS by two different laboratories independently. Since then, several optimized removal conditions for SPS have been described, with the most relevant being 20% piperidine in DMF, which is the most common; 1-5% DBU in DMF; morpholine-DMF (1:1)60or 2% HOBt; 2%hexamethyleneimine; and 25% N-methylpyrrolidine in DMSO-NMP (1:1), with the latter method leaving thioester sintact. The addition of a relatively small amount of HOBt to the piperidine solution [0.1 M HOBt in piperidine-DMF(2:8)] reduces the formation of aspartimide in the sequences prone to this side reaction. Fmoc R-amino protection has been used for the SPS of several relevant peptides using the so-called Fmoc/tBu strategy, with the production in Tm scale of the T20 peptide being one of the most important examples. Nevertheless,the low solubility of some Fmoc derivatives in the most commonly used solvents for SPPS has stimulated the search for new base-labile protecting groups.

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